The neonatal encephalopathy (NEWS) is a malformation of the cerebellum caused by a mutation in the CFA36 gene in poodles. This gene encodes the activating transcription factor 2 (ATF-2). If homozygous, dogs posses a smaller, frequently dysplastic cerebellum. Affected puppies are relatively small and weak and they often die within the first weeks of their live. Those surviving this phase develop ataxia and tremor and by 4 to 6 weeks of age severe generalized tonic-clonic seizures which can't be treated therapeutically. None of them survived to eighth week of life.
The DNA test is performed out of EDTA blood or buccal swabs. Required swabs can be ordered free of charge. (Buccal swab order-form). If a swab is sent in, possibly the genetic material is not sufficient to run the test. In this case it would be best to send in an EDTA blood sample.
Please send in your sample together with the lab order genetic. Results will be transmitted optionally via post, fax or email. After completion of the test you will receive a separate invoice. Payment can be made via credit card or bank transfer. Breeding club discounts apply if a copy of the membership card is sent together with the respective samples. Due to administrative reasons the invoiced price can not be altered subsequently.