The Progressive Retinal Atrophy as an inherited form leads to a degeneration of the retina and results in blindness. The Retina which is composed of photoreceptor cells as well as nerve cells covers the back inside wall of the eye and is responsible for image formation. The photoreceptor cells can be divided into rods or cones depending on their function. The rod cells are specialised for the mesopic vision and contrast sensitivity. The con cells are responsible for color vision. The prcd-PRA causes initially a loss of function of the rod cells accompanied by night blindness. At later stages the cone cells become affected leading to a complete blindness of the dog. Age of onset of clinical symptoms is typically in early adolescence or early adulthood. However, the onset of the disease may vary among different dog breeds.
American Cocker Spaniel, American Eskimo Dog, Australian Cattle Dog, Australian Shepherd, Australian Stumpy Tail Cattle Dog, Bolonka Zwetna, Chesapeake Bay Retriever, Chinese Crested, English Cocker Spaniel, English Shepherd, Entlebucher Mountain Dog, Finnish Lapphund, German Spitz, Gigant Schnauzer, Golden Retriever, Karelian Beardog, Kuvasz, Labradoodle, Labrador Retriever, Lapponian Herder, Markiesje, Norwegian Elkhound, Nova Scotia Duck Tolling Retriever, Portuguese Water Dog, Poodle, Schipperke, Silky Terrier, Spanish Water Dog, Swedish Lapphund, Wäller, Yorkshire Terrier
Optigen: 4-6 weeks after arrival of the sample in the lab
The DNA test is performed out of EDTA blood or buccal swabs. Required swabs can be ordered free of charge. (Buccal swab order-form). If a swab is sent in, possibly the genetic material is not sufficient to run the test. In this case it would be best to send in an EDTA blood sample.
Please send in your sample together with the lab order genetic. Results will be transmitted optionally via post, fax or email. After completion of the test you will receive a separate invoice. Payment can be made via credit card or bank transfer. Breeding club discounts apply if a copy of the membership card is sent together with the respective samples. Due to administrative reasons the invoiced price can not be altered subsequently.